| 1 | E00 | ESRI | ESRI Map Format Export |
| 2 | E01 | Guidance Software | EnCase Image Format |
| 3 | E3S | Zuken | E3.series Project |
| 4 | EAF | N/A | ELAN Annotation Format |
| 5 | EAP | N/A | Adobe Photoshop Exposure Format |
|
| 6 | EAR | Oracle | Java Enterprise Archive Format |
| 7 | EASM | Dassault Systemes | EDrawings Assembly Format |
| 8 | EASMX | Microsoft Corporation | XPS Document |
| 9 | EBQ | N/A | CITE Electronic Bill Of Quantities |
| 10 | EBS | Psychology Software Tools | E-Run 1.x Script |
| 11 | EC3 | Dolby Laboratories | Dolby Digital AC3 Sound Format |
| 12 | ECC | dvdisaster | Dvdisaster Error Correction Format |
| 13 | ECF | Microsoft | Outlook Add-in |
| 14 | ECG | Neozap | ECG Electrocardiography |
| 15 | ECM | Neill Corlett | ECM Disc Image |
| 16 | ECORE | The Eclipse Foundation | Kermeta Ecore Diagram |
| 17 | ECOREDIAG | The Eclipse Foundation | Kermeta Ecore Diagram Information |
| 18 | ECSV | N/A | Encapsulated Comma Separated Value |
| 19 | ECW | ERDAS | Enhanced Compression Wavelet Image |
| 20 | ED | Monolith Productions, Inc. | LithTech Game Level |
| 21 | ED2K | eMule-Project | EDonkey Download Link |
| 22 | EDB | Microsoft | Exchange Information Store Database |
| 23 | EDI | N/A | Electronic Data Interchange Format |
| 24 | EDML | Adobe Systems | Adobe Extension Data Markup Language Document |
| 25 | EDN | Adobe | Acrobat Document Format |
| 26 | EDR | BALARAD, s.r.o. | Embird Color Palette |
| 27 | EDRW | Dassault Systemes | SolidWorks EDrawings Format |
| 28 | EDRWX | Microsoft | XPS Drawing Document |
| 29 | EEB | Corel Corporation | Corel WordPerfect Equation Editor Button Bar |
| 30 | EFA | N/A | Ensoniq ASR Format |
| 31 | EFE | E-Mu | Ensoniq EPS Format |
| 32 | EFI | UEFI Forum | Extensible Firmware Interface Format |
| 33 | EFIRES | Apple | EFI Image Format |
| 34 | EFW | Computer Associates | Renamed Zip Or Executable Format |
| 35 | EFX | j2 Global Communications | EFax Document |
| 36 | EGG-INFO | N/A | Python Egg |
| 37 | EGGP | Adobe Systems Incorporated | Adobe After Effects Project |
| 38 | EIA | N/A | Excellon |
| 39 | EIP | Phase One | Enhanced Image Package Format |
| 40 | EL | The GNU Project | Emacs Lisp Code Format |
| 41 | ELF | Unix System Laboratories | ELF Executable Format |
| 42 | EM | Adobe Systems | Encore Menu Template |
| 43 | EMAIL | Microsoft | Outlook Express Email Message |
| 44 | EMB | Everest | EMBL Nucleotide Format |
| 45 | EMBB | N/A | Middle Earth: Shadow of Mordor game data |
| 46 | EMBL | European Molecular Biology Laboratory | EMBL Sequence Data File |
| 47 | EMF | Microsoft | Enhanced Windows Metafile |
| 48 | EML | Microsoft | E-Mail Message |
| 49 | EMLX | Apple | Mail Message |
| 50 | EMLXPART | N/A | Mail Message Attachment |
| 51 | EMO | Microsoft Corporation | Emoticon |
| 52 | EMT | Epic Games, Inc. | Unreal Engine Emitter |
| 53 | EMULECOLLECTION | eMule | EMule Data Format |
| 54 | EMZ | Microsoft | Windows Compressed Enhanced Metafile |
| 55 | EN | N/A | Generic |
| 56 | ENC2 | Samsung Group | Samsung Galaxy Firmware Update |
| 57 | ENC4 | N/A | Samsung Galaxy encrypted firmware update |
| 58 | ENCIPHERED | N/A | Malware (ransomware) Encoded |
| 59 | ENCRYPTED | N/A | Crypren Ransomware Encrypted File |
| 60 | ENEWS | N/A | Generic |
| 61 | ENG | N/A | English Language Localization Format |
| 62 | ENL | Thomson Reuters | EndNote Library |
| 63 | ENT | N/A | External Entity |
| 64 | ENTITLEMENTS | Apple | Mac App Sandboxing Entitlements Format |
| 65 | ENV | Now Software | Adobe Dictionary Data Format |
| 66 | ENW | Thomson Reuters | EndNote Import Format |
| 67 | EOT | Microsoft | Embedded OpenType Font Format |
| 68 | EPF | Adobe | EPSF Encapsulated Postscript Image Format |
| 69 | EPI | Green Eclipse | Express Publisher Encapsulated Postscript Format |
| 70 | EPIBRW | N/A | Web Format Location |
| 71 | EPME | N/A | Renamed HJSplit Split WinRAR Archive |
| 72 | EPP | Just Great Software Co. Ltd. | EditPad Pro Project Format |
| 73 | EPRT | SolidWorks Corporation | SolidWorks EDrawing Part |
| 74 | EPRTX | Microsoft Corporation | Microsoft XPS Document Related |
| 75 | EPS | Adobe Systems | Encapsulated PostScript Format |
| 76 | EPS2 | N/A | Adobe Level II Encapsulated PostScript |
| 77 | EPS3 | Adobe Systems Incorporated | Encapsulated PostScript Level 3 |
| 78 | EPSF | Adobe Systems | Encapsulated PostScript Format |
| 79 | EPSI | Adobe Systems Incorporated | Adobe Encapsulated PostScript Interchange Format |
| 80 | EPSP | Adobe Systems Incorporated | Adobe Encapsulated PostScript |
| 81 | EPT | N/A | Adobe Encapsulated PostScript Interchange Format With TIFF Preview |
| 82 | EPUB | IDPF | Open EBook Format |
| 83 | EQF | Nullsoft | Winamp Equalizer Preset Format |
| 84 | EQN | N/A | Corel WordPerfect Equation Format |
| 85 | ERBSQL | Ruby community | Ruby SQL |
| 86 | ERF | EPSON | Epson Camera RAW Format |
| 87 | ERR | N/A | Error Log Format |
| 88 | ERUBIS | kuwata-lab | Erubis Script |
| 89 | ERX | N/A | ER Data Model |
| 90 | ER_ | Microsoft Corporation | Microsoft Winhelp Compressed |
| 91 | ES6 | N/A | JavaScript source code |
| 92 | ESCO | Nokia Corporation | Nokia Lumia Windows Phone 7 Firmware |
| 93 | ESD | AutoData Systems | ExpertScan Survey Document Format |
| 94 | ESF | The Creative Assembly | Total War Campaign Settings |
| 95 | ESLOCK | ES APP Group | ES File Explorer File Manager Encrypted File |
| 96 | ESM | Bethesda Softworks | Elder Scrolls Master Format |
| 97 | ESN | Microsoft Corporation | Windows XP System32 |
| 98 | ESPF | Adobe Systems Incorporated | Encapsulated PostScript |
| 99 | EST | Microsoft | Streets & Trips Map Format |
| 100 | ETI | Communications Research Centre Canada | ETI (Ensemble Transport Interface) Stream |
| 101 | ETL | Microsoft | Microsoft Event Trace Log Format |
| 102 | ETX | N/A | Setext Structure Enhanced Text Format |
| 103 | EUF | Microsoft | Private Character Editor Format |
| 104 | EVD | Rockstar Games, Inc. | Grand Theft Auto IV Vehicle Extended Data |
| 105 | EVENT | Corel | Corel Cataloged Folder Format |
| 106 | EVM | Microsoft Corporation | Windows Vista Session Configuration |
| 107 | EVO | EVOGH | HD DVD Video Format |
| 108 | EVT | Microsoft | Windows Event Viewer Log Format |
| 109 | EVTX | Microsoft | Windows 7 Event Log Format |
| 110 | EVX | Caltech | EVO Record |
| 111 | EVY | Corel | Envoy Format |
| 112 | EVZ | Caltech | EVO Compressed Record |
| 113 | EX01 | Guidance Software | EnCase Evidence Image File |
| 114 | EXC | Microsoft | Microsoft Word Exclusion Dictionary Format |
| 115 | EXD | Microsoft | Control Information Cache Format |
| 116 | EXE | Microsoft | Windows Executable Format |
| 117 | EXEC | N/A | Unix executable file |
| 118 | EXE_0002 | N/A | Microsoft Outlook Inbox Repair Tool update |
| 119 | EXH | Electronic Arts, Inc. | NHL Game Exhibition Roster |
| 120 | EXIF | N/A | Exchangeable Image Information Format |
| 121 | EXP | N/A | Symbols Export Format |
| 122 | EXPORTEDUI | Microsoft Corporation | Microsoft Office Import Customization |
| 123 | EXR | Industrial Light & Magic | OpenEXR Image |
| 124 | EXS | Apple | Apple Logic EXS24 Instrument Format |
| 125 | EXSD | The Eclipse Foundation | Eclipse IDE Extension Point Schema |
| 126 | EXTRA | Mozilla | Mozilla Firefox Crash Report Format |
| 127 | EXX | IBM | IBM Linkway MsgPut Format |
| 128 | EXY | N/A | Eltac Embroidery Format |
| 129 | EX_ | Microsoft | Compressed Executable Format |
| 130 | EZE | N/A | ErZorScript Source |
| 131 | EZT | Microsoft | Worm.Win32.AutoRun.ezt Format |
| 132 | EZZ | N/A | Generic |