| 1 | Z | N/A | Unix Compressed Format |
| 2 | Z01 | Corel | WinZip First Split Zip Format |
| 3 | Z02 | Corel | WinZip Second Split Zip Format |
| 4 | Z03 | Corel | WinZip Third Split Zip Format |
| 5 | Z04 | Corel | WinZip Fourth Split Zip Format |
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| 6 | Z05 | WinZip Computing, S.L. | Split Multi-volume ZIP Compressed Format Archive (part 6) |
| 7 | Z06 | WinZip Computing, S.L. | Split Multi-volume ZIP Compressed Format Archive (part 7) |
| 8 | Z07 | WinZip Computing, S.L. | Split Multi-volume ZIP Compressed Format Archive (part 8) |
| 9 | Z08 | WinZip Computing, S.L. | Split Multi-volume ZIP Compressed Format Archive (part 9) |
| 10 | Z09 | WinZip Computing, S.L. | Split Multi-volume ZIP Compressed Format Archive (part 10) |
| 11 | Z12 | WinZip Computing, S.L. | Split Multi-volume ZIP Compressed Format Archive (part 13) |
| 12 | Z13 | WinZip Computing, S.L. | Split Multi-volume ZIP Compressed Format Archive (part 14) |
| 13 | Z15 | WinZip Computing, S.L. | Split Multi-volume ZIP Compressed Format Archive (part 16) |
| 14 | Z16 | WinZip Computing, S.L. | Split Multi-volume ZIP Compressed Format Archive (part 17) |
| 15 | Z18 | WinZip Computing, S.L. | Split Multi-volume ZIP Compressed Format Archive (part 19) |
| 16 | Z19 | WinZip Computing, S.L. | Split Multi-volume ZIP Compressed Format Archive (part 20) |
| 17 | Z64 | Harrison Electronics, Inc. | Nintendo 64 Game ROM |
| 18 | Z80 | Texas Instruments | ZX Spectrum Emulator Memory Snapshot |
| 19 | Z96 | ConeXware, Inc. | PowerArchiver ZIP Multi-volume Archive |
| 20 | ZA | Destineer Publishing Corp. | Game |
| 21 | ZAB | WinZip Computing, S.L. | Zipped Audio Book |
| 22 | ZAP | Microsoft | Zero Administration Package Format |
| 23 | ZARGO | N/A | ArgoUML Model |
| 24 | ZASM | Xeno Innovations, Inc. | Zero Compiler Assembly Source |
| 25 | ZAVE | N/A | QuarkXpress IPad Document |
| 26 | ZBM | Jean-loup Gailly and Mark Adler | Zlib Compressed Bitmap |
| 27 | ZBR | ZONER, Inc. | Zoner Zebra Metafile |
| 28 | ZCLS | Xeno Innovations, Inc. | Zero Compiler Class |
| 29 | ZDCT | Adobe Systems | Adobe Language Format |
| 30 | ZDS | GZDoom | DVDSubber DVD Subtitles And DVD Scripts Format |
| 31 | ZED | BitTorrent, Inc. | BitTorrent Metainfo |
| 32 | ZEG | N/A | ZeroG Subtitles Format |
| 33 | ZERO | Xeno Innovations, Inc. | Zero Compiler Project |
| 34 | ZFS | NavisWorks | Z+F Scan |
| 35 | ZGL | N/A | XGL Compressed Document |
| 36 | ZI | PKWARE | Renamed Zip Format |
| 37 | ZIP | Phil Katz | Zipped Format |
| 38 | ZIPFS | ValuSoft | 18 Wheels Of Steel: Across America Game |
| 39 | ZIPX | Corel | Extended Zip Format |
| 40 | ZIX | WinZix | WinZix Compressed Format |
| 41 | ZLIB | Jean-loup Gailly and Mark Adler | Zlib Archive |
| 42 | ZMF | ZONER, Inc. | Zoner Metafile |
| 43 | ZOO | N/A | Zoo Compressed Format |
| 44 | ZPL | Microsoft | Zune Playlist |
| 45 | ZSH | N/A | Unix Shell Script |
| 46 | ZSRC | Xeno Innovations, Inc. | Zero Source |
| 47 | ZST | ZSNES | ZSNES Save Format |
| 48 | ZTD | Microsoft | Zoo Tycoon Data Archive |
| 49 | ZUL | Potix | ZK User Interface Format |
| 50 | ZVI | Carl Zeiss AG | Carl Zeiss AxioVision Saved Microscope Image |
| 51 | ZVR | SAFA Media | SAFA Media Audio Format |
| 52 | ZVZ | N/A | Malware Format |
| 53 | ZX01 | WinZip Computing, S.L. | Extended ZIP Split Archive |
| 54 | ZX02 | WinZip Computing, S.L. | Extended ZIP Split Archive |
| 55 | ZXP | Adobe Systems | Extension Manager Package |
